? NUS - National University of Singapor

Publications - Micro/nanofluidics and Lab-on-a-chip


  1. Compaction and condensation of DNA mediated by the C-Cterminal domain of Hfq, Antoine Malabirade, Kai Jiang, Krzysztof Kubiak, Alvaro Diaz-Mendoza, Fan Liu, Jeroen A. van Kan, Jean-Francois Berret, Veronique Arluison and Johan R.C. van der Maarel, Nucleic Acids Research 45 (2017) 7299-7308.

  2. High aspect ratio channels in glass and porous silicon, H.D. Liang, Z.Y. Dang, J.F. Wua, J.A. van Kan, S. Qureshi, M.D. Ynsa, V. Torres-Costa, A. Maira, T.V. Venkatesan, M.B.H. Breese, Nuclear Instruments & Methods in Physics Research Section B 394 (2017) 1-5


  1. Effects of Hfq on the conformation and compaction of DNA, Johan R. C. van der Maarel, Kai Jiang, Veronique Arluison, JA van Kan Biophysics Journal 110 (2016) 561A-561A.

  2. Separation of superparamagnetic particles through ratcheted Brownian motion and periodically switching magnetic fields, F. Liu, L. Jiang, H. M. Tan, A. Yadav, P. Biswas, J. R. C. van der Maarel, C. A. Nijhuis, J. A. van Kan, Biomicrofluidics 10 (2016) 064105.


  1. Yuanjun Yan, Daryl Boey, Li Theng Ng, Jan Gruber, Andrew Bettiol, Nitish Thakor, Chia-Hung Chen, Continuous-flow C. elegans fluorescence expression analysis with real-time image processing through microfluidics, Biosensors and Bioelectronics Volume 77, 15 March 2016, 428-434

  2. Kai Jiang, Ce Zhang, Durgarao Guttula, Fan Liu, Jeroen A. van Kan, Christophe Lavelle, Krzysztof Kubiak, Alain Lapp, Veronique Arluison, and Johan R. C. van der Maarel, Effects of Hfq on the conformation and compaction of DNA, Nucleic Acids Research 43 (2015) 4332-4341


  1. Yuanjun Yan, Li Fang Ng, Li Theng Ng, Kwan Bum Choi, Jan Gruber, Andrew A. Bettiol and Nitish V. Thakor, A continuous-flow C. elegans sorting system with integrated optical fiber detection and laminar flow switching, Lab on a Chip 14 (2014) 4000-4006

  2. B. del Rosal, C. Sun, Y. Yan, M.D. Mackenzie, C. Lu, A. A. Bettiol, A.K. Kar and D. Jaque, Flow effects in the laser-induced thermal loading of optical traps and optofluidic devices, Optics Express Vol. 22, Issue 20, pp. 23938-23954 (2014)

  3. J.R.C. van der Maarel, Ce Zhang, and J.A. van Kan, A nanochannel platform for single DNA studies: from crowding, protein DNA interaction, to sequencing of genomic information, Israel Journal of Chemistry (2014) DOI: 10.1002/ijch.201400091


  1. C Zhang, A Hernandez-Garcia, K Jiang, Z Gong, D Guttula, SY Ng, PP Malar, JA van Kan, Liang Dai, PS Doyle, R de Vries, and JRC van der Maarel, Amplified stretch of bottlebrush-coated DNA in nanofluidic channels, Nucleic Acids Research, 41 (2013) e189 (8 pages).

  2. Fan Liu, Kheng Boon Tan, M.P. Malar, S. K. Bikkarolla, J.A. van Kan, Fabrication of nickel molds using proton beam writing for micro/nano fluidic devices, Microelectronic Engineering, 102 (2013) 36-39.

  3. A, Ce Zhang, Kai Jiang, Fan Liu, Patrick S. Doyle, Jeroen A. van Kan and Johan R.C. van der Maarlel, nanofluidic device for single molecule studies with in situ control of environmental solution conditions, Lab on Chip 13 (2013) 2821-2826.

  4. Ce Zhang, Durgarao Guttula, Fan Liu, Piravi Malar, Siow Yee Ng, Liang Dai, Patrick Doyle, Jeroen Anton van Kan and Johan van der Maarel, Effect of H-NS on the elongation and compaction of single DNA molecules in a nanospace, Soft Matter, 9 (2013) 9593-9601


  1. Simon Verleger, Andrej Grimm, Christian Kreuter, Huei Ming Tan, Jeroen A. van Kan, Artur Erbe, Elke Scheera and Johan R. C. van der Maarel, A single-channel microparticle sieve based on Brownian ratchets,Lab Chip, 2012, 12, 1238

  2. Jeroen A. van Kan , Ce Zhang , Piravi Perumal Malar , and Johan R. C. van der Maarel, High throughput fabrication of disposable nanofluidic lab-on-chip devices for single molecule studies,Biomicrofluidics 6, 036502 (2012)

  3. Ce Zhang, Zongying Gong,Durgarao Guttula, Piravi P. Malar, Jeroen A. van Kan, Patrick S. Doyle and Johan R. C. van der Maarel, Nanouidic Compaction of DNA by Like-Charged Protein,J. Phys. Chem. B 2012, 116, 3031-3036

  4. S. Homhuan, B. Zhang, F.-S. Sheu, A. A. Bettiol and F. Watt, Single-cell electroporation using proton beam fabricated biochips, Biomedical Microdevices 14 (2012) 533-540


  1. J. A. van Kan, P. G. Shao, Y. H. Wang and P. Malar, Proton beam writing a platform technology for high quality three dimensional metal mold fabrication for nanofluidic applications, Microsystem Technologies (2011) 17:1519-1527

  2. Siew-Kit Hoi, Xiao Chen, Vanga S. Kumar, Sureerat Homhuan, Chorng-Haur Sow and Andrew A. Bettiol, A microfluidic chip with integrated colloidal crystal for online optical analysis, Advanced Functional Materials 21 (2011) 2847-2853


  1. Siew-Kit Hoi, Zhi-Bin Hu, Yuanjun Yan, Chorng-Haur Sow, and Andrew A. Bettiol, A microfluidic device with integrated optics for microparticle switching, Applied Physics Letters 97 (2010) 183501.

  2. Siew-Kit Hoi, Vuong Hoang Kim, Nguyen Manh Huy, Chorng-Haur Sow, Yueh-Sheng Ow, Andrew A. Bettiol, Passive optical separation and enrichment of cells by size difference, Biomicrofluidics 4 (2010) 044111


  1. S.-K. Hoi, C. Udalagama, C.-H. Sow, F. Watt and A.A. Bettiol, Microfluidic sorting system based on optical force switching, Applied Physics B: Lasers and Optics 97 (2009) 859-865

  2. Fabrication of nanochannels on polymer thin film, Phan VN (Phan, Vinh-Nguyen), Abgrall P (Abgrall, Patrick), Nguyen NT (Nguyen, Nam-Trung), Shao PG (Shao, Peige), Van Kan JA (Van Kan, Jeroen Anton), ICNMM 2009, PTS A-B, Pages: 921-925, 2009.